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Noticias de Crohn - Copy.png

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An investigational JAK1 inhibitor was effective and reasonably safe in treating patients with refractory Crohn's disease in a mid-stage, dose-ranging trial, a researcher reported here.

 

Treatment with AbbVie's oral drug ABT-494, now dubbed upadacitinib, for 16 weeks produced clinical remission rates of up to 27% depending on the dose, compared with 11% in a placebo group, said William Sandborn, MD, of the University of California San Diego, during a late-breaker session at Digestive Disease Week.

 

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